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Wednesday, November 14, 2012

Low HDL cholesterol levels increase the risk of gastric cancer.

This study was published in the Journal of Gastroenterology and Hepatology 2012 Oct;27(10):1635-40
 
Study title and authors:
Evaluation of serum high-density lipoprotein cholesterol levels as a prognostic factor in gastric cancer patients.
Tamura T, Inagawa S, Hisakura K, Enomoto T, Ohkohchi N.
Department of Surgery, Doctoral Program in Clinical Science, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan.
 
This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/22647147

The study investigated the relationship between high-density lipoprotein (HDL) cholesterol levels and the risk of gastric cancer. The study included 184 patients who had undergone gastrectomy (gastrectomy is a partial or full surgical removal of the stomach).

The patients were divided into two groups:
(i) Normal levels of HDL cholesterol group.
(ii) Low levels of HDL cholesterol group.

The study found:
(a) In the low HDL cholesterol group the cancer had significantly increased in the lymphatic and vascular systems.
(b) The prognosis of the patients in the normal HDL cholesterol group was significantly better than those in the low HDL cholesterol group.

The results of the study show a correlation between low HDL cholesterol levels and an increased risk of gastric cancer.

A diet high in saturated fat raises HDL cholesterol levels. See here here and here.

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