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Tuesday, January 29, 2013

Statins increase the risk of chronic muscle diseases by 286%

This study was published in the Annals of the Rheumatic Diseases 2008 May;67(5):614-9
 
Study title and authors:
Increased exposure to statins in patients developing chronic muscle diseases: a 2-year retrospective study.
Sailler L, Pereira C, Bagheri A, Uro-Coste E, Roussel B, Adoue D, Fournie B, Laroche M, Zabraniecki L, Cintas P, Arlet P, Lapeyre-Mestre M, Montastruc JL.
Unit of Pharmacoepidemiology, EA 3696, Clinical Pharmacology Department, Paul Sabatier University, 37 Allées Jules Guesdes, 31000 Toulouse, France. sailler.l@chu-toulouse.fr
 
This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/17768174

This study evaluated the association between chronic muscle diseases and prior exposure to cholesterol lowering drugs. The study, which lasted for two years, included 37 patients with chronic muscle diseases such as dermatomyositis and polymyositis who were compared to 185 control subjects.

The study found that those who were exposured to statins had a 286% increased risk of dermatomyositis and polymyositis.

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