This study was published in Circulation 1990 Dec;82(6):1916-24
Study title and authors:
An analysis of randomized trials evaluating the effect of cholesterol reduction on total mortality and coronary heart disease incidence.
Holme I.
Life Insurance Companies' Institute for Medical Statistics, Ullevaal Hospital, Oslo, Norway.
This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/2242517
The study investigated the relationship between cholesterol reduction and death rates by analysing the results of 19 randomized clinical cholesterol reduction intervention trials (by drugs and diet). The 19 trials included 103,598 subjects and lasted between two and ten years.
The study found that those who had the cholesterol lowering treatment had a 3.7% increased risk of death compared to those who had no cholesterol lowering treatment.
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